719 research outputs found

    Does the Presence of a Learning Disability Elicit a Stigmatization?

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    Aims: To determine whether or not a Learning Disability(LD) label leads to stigmatization. Study Design: This research used a 2(sex of participant) x 2(LD label)x 2 (Sex of stimulus person) factorial design. Place and Duration of Study: Bucknell University, between October 2010 and April 2011. Methodology: Sample: We included 200 participants (137 women and 63 men, ranging in age from 18 – 75 years, M = 26.41. Participants rated the stimulus individual on 27 personality traits, 8 Life success measures, and the Big-5 personality dimensions. Also, participants completed a Social Desirability measure. Results: A MANOVA revealed a main effect for the Learning Disability description, F(6, 185) = 6.41 p\u3c .0001, eta2 = .17,for the Big-5 personality dimensions, Emotional Stability, F(1, 185) = 13.39, p \u3c .001, eta2 = .066, and Openness to Experiences F(1,185) = 7.12, p\u3c .008, eta2 = .036.Stimulus individuals described as having a learning disability were perceived as being less emotionally stable and more open to experiences than those described as not having a learning disability. Another MANOVA revealed a main effect for having a disability or not, F(8, 183) = 4.29, p\u3c .0001, eta2 = .158, for the Life Success items, Attractiveness, F(1, 198) = 16.63, p\u3c .0001, eta2 = .080, and Future Success,F(1, 198) = 4.57, p\u3c .034, eta2 = .023. Stimulus individuals described as having a learning disability were perceived as being less attractive and with less potential for success than those described as not having a learning disability. Conclusion: The results of this research provide evidence that a bias exists toward those who have learning disabilities. The mere presence of an LD label had the ability to cause a differential perception of those with LDs and those without LDs

    Wildlife conservation : a 4-H club activity

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    Cooperative Extension Work in Agriculture and Home Economics, University of Missouri, College of Agriculture and the United States Department of Agriculture cooperating."January, 1941."Title from cover.Form at end: Annual report and record of 4-H Club Wildlife Activities. Original, folded in back of book, is 21 x 28 cm

    An Evaluation of a Behaviour Assessment to Determine the Suitability of Shelter Dogs for Rehoming

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    We evaluated a scheme for assessing shelter dog behaviour, which used 28 tests and rated responses from 0 (positive response) to 5 (fear, tonic immobility, or escape attempts). The assessment was evaluated for 236 dogs, and was repeated by a different assessor for 39 dogs approximately 80 days after rehoming to determine relevance of individual test components. A new owner survey evaluated satisfaction with the dog. A total of 130 of 236 dogs passed (score ≤ 70), 24 scored 71–80 (referred for behavioural modification), and 82 (score > 80) failed. Scores were mainly unaffected by dog type and environmental variables, but decreased if dog faeces from a previous test was present in the arena during a test. Shelter tests only correlated with repeat tests if there was no direct contact with assessors. Adopters were satisfied with their dogs, despite reporting some behaviour problems. The shelter assessment was therefore robust against most outside influences but did not predict responses to people well

    Rapid Bacterial Testing for Spacecraft Water

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    Evaluations of the fluorogenic stains and probes will continue. E. coli 0157:H7 will be used as the reference strain for optimizing protocols. We anticipate the continued use of the fluorescent antibodies (TRITC and FITC labeled) in conjunction with CTC, Rhl23, DiBAC4(3), DAPI and acridine orange. Chemunex, the manufacturer of the ChemScan analyzer system, also makes a fluorogenic probe, Chemchrome B, which will be incorporated into the suite of probes to evaluate once their system is on site. Regardless of the combination of stains and probes all will be evaluated on membrane filters. Development of a FISH protocol that will be applicable to our conditions will be continued. Complimentary 16s rRNA probes to Ps. aeruginosa and currently in our laboratory will be evaluated first. Once this protocol has been adequately optimized other probes will be ordered for u a select number of other species. Currently, protocols to evaluate the effects of disinfection and the resulting lethality, injury on stain and/or probe specificity and reliability are being developed. E. coli 0157:H7 is the reference strain and chlorine the disinfectant the reference protocol is being developed around. Upon completion of this work, the resulting protocol will be extended to other species and disinfectants (e.g., iodine). Similar disinfectant experiments will then be conducted on the same species after starvation to evaluate the effects of starvation on disinfection resistance and the applicability of the stains and probes. Development of the immunomagnetic separation system will continue. Combined with the rapid methods described above, with enumeration by the ChemScan, we anticipate that this will provide a highly sensitive technique for the detection of specific, active bacteria

    Life Beneath Glacial Ice - Earth(!) Mars(?) Europa(?)

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    We are investigating a set of cold springs that deposit sulfur and carbonate minerals on the surface of a Canadian arctic glacier. The spring waters and mineral deposits contain microorganisms, as well as clear evidence that biological processes mediate subglacial chemistry, mineralogy, and isotope fractionation . The formation of native sulphur and associated deposits are related to bacterially mediated reduction and oxidation of sulphur below the glacier. A non-volcanic, topography driven geothermal system, harboring a microbiological community, operates in an extremely cold environment and discharges through solid ice. Microbial life can thus exist in isolated geothermal refuges despite long-term subfreezing surface conditions. Earth history includes several periods of essentially total glaciation. lee in the near subsurface of Mars may have discharged liquid water in the recent past Cracks in the ice crust of Europa have apparently allowed the release of water to the surface. Chemolithotrophic bacteria, such as those in the Canadian springs, could have survived beneath the ice of "Snowball Earth", and life forms with similar characteristics might exist beneath the ice of Mars or Europa. Discharges of water from such refuges may have brought to the surface living microbes, as well as longlasting chemical, mineralogical, and isotopic indications of subsurface life

    Damage of woven composite under tensile and shear stress using infrared thermography and micrographic cuts

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    Infrared thermography was used to study damage developing in woven fabrics. Two different experiments were performed, a ±45° tensile test and a rail shear test. These two different types of tests show different damage scenarios, even if the shear stress/strain curves are similar. The ±45° tension test shows matrix hardening and matrix cracking whereas the rail shear test shows only matrix hardening. The infrared thermography was used to perform an energy balance, which enabled the visualization of the portion of dissipated energy caused by matrix cracking. The results showed that when the resin is subjected to pure shear, a larger amount of energy is stored by the material, whereas when the resin is subjected to hydrostatic pressure, the main part of mechanical energy is dissipated as heat

    Do quasi-regular structures really exist in the solar photosphere? I. Observational evidence

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    Two series of solar-granulation images -- the La Palma series of 5 June 1993 and the SOHO MDI series of 17--18 January 1997 -- are analysed both qualitatively and quantitatively. New evidence is presented for the existence of long-lived, quasi-regular structures (first reported by Getling and Brandt (2002)), which no longer appear unusual in images averaged over 1--2-h time intervals. Such structures appear as families of light and dark concentric rings or families of light and dark parallel strips (``ridges'' and ``trenches'' in the brightness distributions). In some cases, rings are combined with radial ``spokes'' and can thus form ``web'' patterns. The characteristic width of a ridge or trench is somewhat larger than the typical size of granules. Running-average movies constructed from the series of images are used to seek such structures. An algorithm is developed to obtain, for automatically selected centres, the radial distributions of the azimuthally averaged intensity, which highlight the concentric-ring patterns. We also present a time-averaged granulation image processed with a software package intended for the detection of geological structures in aerospace images. A technique of running-average-based correlations between the brightness variations at various points of the granular field is developed and indications are found for a dynamical link between the emergence and sinking of hot and cool parcels of the solar plasma. In particular, such a correlation analysis confirms our suggestion that granules -- overheated blobs -- may repeatedly emerge on the solar surface. Based on our study, the critical remarks by Rast (2002) on the original paper by Getling and Brandt (2002) can be dismissed.Comment: 21 page, 8 figures; accepted by "Solar Physics

    Lubiprostone ameliorates the cystic fibrosis mouse intestinal phenotype

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    <p>Abstract</p> <p>Background</p> <p>Cystic fibrosis (CF) is caused by mutations in the <it>CFTR </it>gene that impair the function of CFTR, a cAMP-regulated anion channel. In the small intestine loss of CFTR function creates a dehydrated, acidic luminal environment which is believed to cause an accumulation of mucus, a phenotype characteristic of CF. CF mice have small intestinal bacterial overgrowth, an altered innate immune response, and impaired intestinal transit. We investigated whether lubiprostone, which can activate the CLC2 Cl<sup>- </sup>channel, would improve the intestinal phenotype in CF mice.</p> <p>Methods</p> <p><it>Cftr<sup>tm1UNC </sup></it>(CF) and wildtype (WT) littermate mice on the C57BL/6J background were used. Lubiprostone (10 μg/kg-day) was administered by gavage for two weeks. Mucus accumulation was estimated from crypt lumen widths in periodic acid-Schiff base, Alcian blue stained sections. Luminal bacterial load was measured by qPCR for the bacterial 16<it>S </it>gene. Gastric emptying and small intestinal transit in fasted mice were assessed using gavaged rhodamine dextran. Gene expression was evaluated by Affymetrix Mouse430 2.0 microarray and qRT-PCR.</p> <p>Results</p> <p>Crypt width in control CF mice was 700% that of WT mice (<it>P </it>< 0.001). Lubiprostone did not affect WT crypt width but, unexpectedly, increased CF crypt width 22% (<it>P </it>= 0.001). Lubiprostone increased bacterial load in WT mice to 490% of WT control levels (<it>P </it>= 0.008). Conversely, lubiprostone decreased bacterial overgrowth in CF mice by 60% (<it>P </it>= 0.005). Lubiprostone increased gastric emptying at 20 min postgavage in both WT (<it>P </it>< 0.001) and CF mice (<it>P </it>< 0.001). Lubiprostone enhanced small intestinal transit in WT mice (<it>P </it>= 0.024) but not in CF mice (<it>P </it>= 0.377). Among other innate immune markers, expression of mast cell genes was elevated 4-to 40-fold in the CF intestine as compared to WT, and lubiprostone treatment of CF mice decreased expression to WT control levels.</p> <p>Conclusions</p> <p>These results indicate that lubiprostone has some benefits for the CF intestinal phenotype, especially on bacterial overgrowth and the innate immune response. The unexpected observation of increased mucus accumulation in the crypts of lubiprostone-treated CF mice suggests the possibility that lubiprostone increases mucus secretion.</p

    Penrose Diagram for a Transient Black Hole

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    A Penrose diagram is constructed for a spatially coherent black hole that smoothly begins an accretion, then excretes symmetrically as measured by a distant observer, with the initial and final states described by a metric of Minkowski form. Coordinate curves on the diagram are computationally derived. Causal relationships between space-time regions are briefly discussed. The life cycle of the black hole demonstrably leaves asymptotic observers in an unaltered Minkowski space-time of uniform conformal scale.Comment: 14 pages, 9 figures, spelling correction

    Damage analysis and fracture toughness evaluation in a thin woven composite laminate under static tension using infrared thermography

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    This work deals with the issue of damage growth in thin woven composite laminates subjected to tensile loading. The conducted tensile tests were monitored on-line with an infrared camera, and tested specimens were analysed using Scanning Electron Microscopy (SEM). Combined with SEM micrographs, observation of heat source fields enabled us to assess the damage sequence. Transverse weft cracking was confirmed to be the main damage mode and fiber breakage was the final damage leading to failure. For cracks which induce little variation of specimen stiffness, the classic “Compliance method” could not be used to compute energy release rate. Hence, we present here a new procedure based on the estimation of heat source fields to calculate the energy release rate associated with transverse weft cracking. The results are then compared to those computed with a simple 3D inverse model of the heat diffusion problem and those presented in the literature
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